The Effects of Solvent Polarity on Hypoglycemic and Hypolipidemic Activities of Portulaca Oleracea and Achillea Eriophora DC Extracts

نویسندگان

چکیده

The influence of solvent polarity for hydroethanol (a), chloroform (b), and carbon tetrachloride (c) on bioactive extraction contents Portulaca oleracea (II) Achillea eriophora DC (III) were evaluated by GC-MS analysis. antidiabetic antilipidemic properties different extracts investigated streptozotocine-induced diabetic rats compared to glibenclamide as well-known chemical drug the treatment diabetes. results indicated that IIa – IIIc, IIIa, IIIb reduced blood serum glucose significantly days 9 especially 16 after induction In addition, LDL cholesterol level was markedly using IIb, IIc IIIc extracts. Serum TG decreased (especially extracts) in animal groups control groups. These can be related more extracted sterols, fatty acids, polyols (or alcohols), phenols flavonoids well antraquinones terpenes polar or non-polar organic solvents aqueous these medicinal herbs.

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ژورنال

عنوان ژورنال: Pharmaceutical Chemistry Journal

سال: 2021

ISSN: ['0091-150X', '1573-9031']

DOI: https://doi.org/10.1007/s11094-021-02350-y